Beilstein J. Org. Chem.2014,10, 2642–2648, doi:10.3762/bjoc.10.276
supercritical CO2, ionic liquids or fluorous phases have been used to immobilize the organometallic catalyst [3][4][5]. Co-solvents, surfactants, amphiphilicphosphanes, molecular receptors, polymers or dispersed particles have also been investigated to favour contacts between the aqueous and the organic
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Graphical Abstract
Scheme 1:
Synthesis of CD-substituted polymers 3a, 3b and 3c.
Beilstein J. Org. Chem.2012,8, 1479–1484, doi:10.3762/bjoc.8.167
increase in the catalytic performances.
Keywords: amphiphilicphosphanes; biphasic system; cyclodextrins; micelles; Introduction
Facing the need of developing a greener chemistry, chemists have recently focused their investigations on clean transformation processes to convert organic molecules into
substrates constitutes a real challenge not completely solved so far. Recently, we showed that an association of cyclodextrins (CDs) and amphiphilicphosphanes could significantly improve the catalytic performances in an aqueous rhodium-catalyzed hydroformylation of higher olefins [6]. Herein we clearly
demonstrate that the beneficial effect of CDs on a catalytic micellar system can be generalized to another reaction and other amphiphilicphosphanes. To this end, we undertook a study using the randomly methylated β-cyclodextrin (RAME-β-CD) as an additive in an aqueous Pd-catalyzed cleavage reaction of allyl